Table 1

Effect of D-Arg, L-Arg and DL-Arg on the growth of transplantable animal tumours
Treatment
 Tumour
 Number of animals
 Daily dose (mg/kg)
 Duration of treatment (days)
 Inhibition %
 Remarks








Treated
 Control



D-Arg1
 Yoshida
 6
 6
 500 p.o.
 12
 50
 p < 0.05
D-Arg 1
 Ehrlich s.c.
 10
 10
 500 i.p.
 10
 20
 p < 0.1
L-Arg3
 Yoshida
 10
 10
 400 i.p.
 10
 -40
 Enhancement p < 0.05
L-Arg3
 Yoshida
 10
 10
 400 p.o.
 9
 -30
 Enhancement p < 0.1
L-Arg2
 Ehrlich s.c.
 10
 10
 500 i.p.
 12
 -40
 Enhancement p < 0.05
DL-Arg3
 Ehrlich s.c.
 10
 10
 500 i.p.
 12
 -
 -

1Serva (USA), 2Ajinomoto (Japan), 3Reanal (Hungary) Animals were sacrificed 24 hours after the last treatment and tumour weight was measured. Inhibition or enhancement is given as per cent of the control tumours. Abbreviations:i. p. – intraperitoneal; p. o. – peroral; s. c. – subcutaneous; Arg – arginine

Szende et al. Cancer Cell International 2001 1:3   doi:10.1186/1475-2867-1-3