Table 1

Inhibiting effect of red microalgal polysaccharides on formation of foci by MuSV-124 and on virus production, as measured by reverse transcriptase (RT) activity

Algal polysaccharide

Virus

ffu₅₀ protection (μg/ml)

RT₅₀ reduction (μg/ml)

Porphyridium sp.

MuSV-124

10

-

MuSV/MuLV

-

5

P. aerugineum

MuSV-124

500

-

MuSV/MuLV

-

200

Rhodella reticulata

MuSV-124

150

-

MuSV/MuLV

-

50

NIH/3T3 cells were infected with MuSV-124 or MuSV/MuLV in the presence of various concentrations of algal polysaccharides. ffu₅₀ protection and RT₅₀ reduction represent the concentration of polysaccharide that offers 50% protection against the formation of foci of malignant cells and 50% reduction of RT activity, respectively. Data represent mean values of five separate experiments.

Talyshinsky et al. Cancer Cell International 2002 2:8   doi:10.1186/1475-2867-2-8