Table 2

Anticancer activity of Pep27 and of its analogues in various cancer cell lines by MTT assay
Peptide
 IC50 (μM)


AML-2
 HL-60
 Jurkat
 SNU-601
 MCF-7
Pep27
 >70
 >70
 >70
 >70
 >70
Pep27anal1
 50
 53
 47
 37
 55
Pep27anal2
 29
 20
 23
 25
 <10
Pep27anal3
 67
 52
 50
 50
 38
Pep27anal4
 50
 51
 46
 37
 29
Pep27anal5
 >70
 >70
 >70
 >70
 >70

AML-2, acute myelogenous leukemia cell line; HL-60, acute promyelocytic leukemia cell line; Jurkat, T cell leukemia cell line; SNU-601, gastric cancer cell line; MCF-7, breast cancer cell line

Lee et al. Cancer Cell International 2005 5:21   doi:10.1186/1475-2867-5-21