Figure 9.

Light microscopy photos of wild-type p53 cell line MEF 12(1) following 10 Gy γ-irradiation. Methanol/glacial acetic acid fixed cells were stained using Hoechst 33258 and visualized using fluorescence microscopy, as described in Material and Methods. Panel A: morphology of MEF 12(1) cells at 40 hours post-irradiation. Panel B: morphology of sham-irradiated MEF 12(1) cells, at time zero.