Figure 1.

Incision of oligonucleotide containing furan lesion. HeLa cells were synchronized and Flow cytometer analysis confirmed their G1 or G2 status. The labeled oligonucleotide was incubated with cell extracts prepared from synchronized G1 or G2 HeLa cells either irradiated or not irradiated. The incision products on the gel were quantified with PhosphorImager to determine percentage cleavage.