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1.

908
Accesses

Review   Open Access Highly Accessed

Role of stem cells in cancer therapy and cancer stem cells: a review

Jayesh Sagar, Boussad Chaib, Kevin Sales, Marc Winslet, Alexander Seifalian Cancer Cell International 2007, 7:9 (4 June 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

2.

630
Accesses

Hypothesis   Open Access

Cancer: a “stem-cell” disease?

Shi-Ming Tu Cancer Cell International 2013, 13:40 (6 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

3.

593
Accesses

Primary research   Open Access Highly Accessed

Endothelial cell pseudopods and angiogenesis of breast cancer tumors

Ivan L Cameron, Nicholas Short, LuZhe Sun, W Elaine Hardman Cancer Cell International 2005, 5:17 (26 May 2005)

Abstract | Full text | PDF | PubMed

4.

581
Accesses

Primary research   Open Access

Targeting PI3K/Akt represses Hypoxia inducible factor-1α activation and sensitizes Rhabdomyosarcoma and Ewing’s sarcoma cells for apoptosis

Mehtap Kilic-Eren, Tulin Boylu, Vedrana Tabor Cancer Cell International 2013, 13:36 (16 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

554
Accesses

Primary research   Open Access

Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay

Jo-Anne de la Mare, Jason N Sterrenberg, Mugdha G Sukhthankar, Maynard T Chiwakata, Denzil R Beukes, Gregory L Blatch, Adrienne L Edkins Cancer Cell International 2013, 13:39 (1 May 2013)

Abstract | Provisional PDF | PubMed

6.

543
Accesses

Hypothesis   Open Access

Li Fraumeni syndrome, cancer and senescence: a new hypothesis

Pan Pantziarka Cancer Cell International 2013, 13:35 (15 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

7.

523
Accesses

Review   Open Access Highly Accessed

Tumor suppressor gene E-cadherin and its role in normal and malignant cells

Nives Pećina-Šlaus Cancer Cell International 2003, 3:17 (14 October 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

521
Accesses

Primary research   Open Access

Activity of histone deacetylase inhibitors and an Aurora kinase inhibitor in BCR-ABL-expressing leukemia cells: Combination of HDAC and Aurora inhibitors in BCR-ABL-expressing cells

Seiichi Okabe, Tetsuzo Tauchi, Yuko Tanaka, Shinya Kimura, Taira Maekawa, Kazuma Ohyashiki Cancer Cell International 2013, 13:32 (4 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

9.

517
Accesses

Primary research   Open Access

Changes in the MALT1-A20-NF-κB expression pattern may be related to T cell dysfunction in AML

Li Shi, Shaohua Chen, Yuhong Lu, Xu Wang, Ling Xu, Fan Zhang, Lijian Yang, Xiuli Wu, Bo Li, Yangqiu Li Cancer Cell International 2013, 13:37 (30 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

10.

513
Accesses

Review   Open Access

Oral squamous cell carcinoma in relation to field precancerisation: pathobiology

Liviu L Feller, Razia RAG Khammissa, Beverly B Kramer, Johan J Lemmer Cancer Cell International 2013, 13:31 (3 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

11.

486
Accesses

Primary research   Open Access

Independent of ErbB1 gene copy number, EGF stimulates migration but is not associated with cell proliferation in non-small cell lung cancer

Camila Lauand, Paula Rezende-Teixeira, Beatriz Araújo Cortez, Evandro Luís de Oliveira Niero, Gláucia Maria Machado-Santelli Cancer Cell International 2013, 13:38 (30 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

12.

455
Accesses

Primary research   Open Access Highly Accessed

Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture

Karen M Imbalzano, Iva Tatarkova, Anthony N Imbalzano, Jeffrey A Nickerson Cancer Cell International 2009, 9:7 (16 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

13.

441
Accesses

Primary research   Open Access Highly Accessed

Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR

Takashi Watanabe, Tomohiro Miura, Yusuke Degawa, Yuna Fujita, Masaaki Inoue, Makoto Kawaguchi, Chie Furihata Cancer Cell International 2010, 10:2 (21 January 2010)

Abstract | Full text | PDF | PubMed

14.

438
Accesses

Primary research   Open Access

Notch1 signaling is involved in regulating Foxp3 expression in T-ALL

Xiaodan Luo, Huo Tan, Yueqiao Zhou, Tiantian Xiao, Chunyan Wang, Yangqiu Li Cancer Cell International 2013, 13:34 (11 April 2013)

Abstract | Provisional PDF | PubMed

15.

431
Accesses

Primary research   Open Access Highly Accessed

The novel mTOR inhibitor CCI-779 (temsirolimus) induces antiproliferative effects through inhibition of mTOR in Bel-7402 liver cancer cells

Shuyu Li, Yan Liang, Manlin Wu, Xiaojing Wang, Haixia Fu, Yuhao Chen, Zhigang Wang Cancer Cell International 2013, 13:30 (28 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

16.

379
Accesses

Primary research   Open Access

Depleting NFAT1 expression inhibits the ability of invasion and migration of human lung cancer cells

Ji-fu Liu, Shou-hua Zhao, Shan-shan Wu Cancer Cell International 2013, 13:41 (12 May 2013)

Abstract | Full text | PDF | PubMed

17.

376
Accesses

Review   Open Access Highly Accessed

Wnt signal transduction pathway and apoptosis: a review

Nives Pećina-Šlaus Cancer Cell International 2010, 10:22 (30 June 2010)

Abstract | Full text | PDF | PubMed

18.

376
Accesses

Primary research   Open Access Highly Accessed

Beclin1 inhibition promotes autophagy and decreases gemcitabine–induced apoptosis in Miapaca2 pancreatic cancer cells

Xiaoshu Li, Jun Yan, Lisheng Wang, Fengjun Xiao, Yuefeng Yang, Xiaozhong Guo, Hua Wang Cancer Cell International 2013, 13:26 (13 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

19.

377
Accesses

Primary research   Open Access

Caspase-2 is involved in cell death induction by taxanes in breast cancer cells

Michael Jelínek, Kamila Balu¿íková, Dana Kopperová, Vlasta N¿mcová-Fürstová, Jan ¿rámek, Julie Fidlerová, Ilaria Zanardi, Iwao Ojima, Jan Ková¿ Cancer Cell International 2013, 13:42 (15 May 2013)

Abstract | Provisional PDF | PubMed

20.

351
Accesses

Primary research   Open Access

Response to microtubule-interacting agents in primary epithelial ovarian cancer cells

Ilenia Pellicciotta, Chia-Ping Huang Yang, Charis A Venditti, Gary L Goldberg, Shohreh Shahabi Cancer Cell International 2013, 13:33 (10 April 2013)

Abstract | Provisional PDF | PubMed

21.

342
Accesses

Primary research   Open Access

EGCG induces human mesothelioma cell death by inducing reactive oxygen species and autophagy

Motohiko Satoh, Yukitoshi Takemura, Hironobu Hamada, Yoshitaka Sekido, Shunichiro Kubota Cancer Cell International 2013, 13:19 (23 February 2013)

Abstract | Full text | PDF | PubMed

22.

341
Accesses

Primary research   Open Access

Mifepristone improves chemo-radiation response in glioblastoma xenografts

Monserrat Llaguno-Munive, Luis Alberto Medina, Rafael Jurado, Mario Romero-Piña, Patricia Garcia-Lopez Cancer Cell International 2013, 13:29 (25 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

23.

338
Accesses

Review   Open Access Highly Accessed

ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal

Cheol-Hee Choi Cancer Cell International 2005, 5:30 (4 October 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

339
Accesses

Hypothesis   Open Access Highly Accessed

Stem cells, senescence, neosis and self-renewal in cancer

Rengaswami Rajaraman, Duane L Guernsey, Murali M Rajaraman, Selva R Rajaraman Cancer Cell International 2006, 6:25 (8 November 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 4 comments

25.

324
Accesses

Primary research   Open Access Highly Accessed

Role of hypoxia and glycolysis in the development of multi-drug resistance in human tumor cells and the establishment of an orthotopic multi-drug resistant tumor model in nude mice using hypoxic pre-conditioning

Lara Milane, Zhenfeng Duan, Mansoor Amiji Cancer Cell International 2011, 11:3 (14 February 2011)

Abstract | Full text | PDF | PubMed

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