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Synthesis and biological activity of some structural modifications of pancratistatin.

Rinner U, Hillebrenner HL, Adams DR, Hudlicky T, Pettit GR.

Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA.

Structurally modified derivatives of 7-deoxypancratistatin have been synthesized and evaluated in cancer cell line inhibition studies.

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PMID: 15125958 [PubMed - indexed for MEDLINE]